FIRST YEAR BIOCHEMISTRY: VITAMINS

"VITAMINS"

TABLE OF SPECIFICATION:

• SEQS: 7.5 Marks
• MCQs: 07 Marks

BOOKS:

·         Lippincott

·         HARPER illustrated biochemistry

·         Medical biochemistry by MUSHTAQ

GUIDELINES:

• Chapter: 28 Lippincott Biochemistry

This complete chapter is to be done thoroughly. First learn the table given at the end of chapter then learn the details.

• Chapter: 44 Harper Biochemistry

Only Fig 44.2(Molecular changes when photon strikes rhodopsin) is included.

IMPORTANT:

• MCQs:

1. Differences in use of vitamin B
2. Vitamin B12 contains Corrin ring with Cobalt.
3. Niacin contains tryptophan.
4. Cobalamin is obtained only from animal sources.
5. Corn based diets causes Pallegara.
6. Biotin contains lysyl residues
7. Vitamin K dependent clotting factors.
8. Deficiency of certain vitamin causes which disease.
9. Isoniazid drug used to treat tuberculosis.

• SEQs:

WATER SOLUBLE VITAMINS:

1. Role of Folic Acid in neural tube defects and anemias.
2. Folate trap hypothesis(imp)
3. Deficiency of Cobalamin and pernicious anemia.
4. Functions of Ascorbic Acid
5. Scenario based questions can come from any disease such as Scurvy, Beriberi, wernicke korsoff syndrome etc.
6. Reactions in which Pyridoxine acts as Coenzyme.
7. Pallegara( three Ds), Hartnup syndrome
8. Niacin role in hyperlipidemia treatment.

FAT SOLUBLE VITAMINS:

1. Scenario Based qs from all fat soluble vitamins can come.
2. Mechanism of action of Vitamin A
3. How Vitamin A is used in Visual Cycle(Fig 28.19 and 28.20)
4. Toxicity and deficiency symptoms of vit A
5. Difference between Rickets and osteomalacia
6. Metabolism and sites of hydroxylation of Vitamin D
7. Functions of Vitamin D
8. Vitamin K role in clotting(imp)
9. Effect of vitamin K on RBC membrane
10. Functions of Vitamin E(imp) (antioxidant, slow down macular degeneration, component of glutathione peroxidase, maintain membrane integrity, chain breaking, boost up immune system, protects RBCs from hemolysis)

• VIVA VOCE:

1. In proff examines asked each student a different vitamin and every detail about that particular vitamin.
2. Vit A visual cycle( walds visual cycle)
3. Vitamin D cycle
4. Folate trap hypothesis
5. Relation of calcitonin and parathyroid hormones.

@Marium Raza and Muhammad Zeeshan